University of California San Francisco

Elizabeth Wick large
Elizabeth
Wick
MD

Professor of Surgery
Division of Surgical Oncology
Vice Chair of Quality and Safety 
Co-chair, Department of Surgery Research Committee

Address

513 Parnassus Avenue, HSW, #1611
San Francisco, CA 94143
United States

Email: [email protected]
Phone: 415-476-3131
Fax: 415-476-8694

    Biography

    Elizabeth C. Wick, M.D. is a professor of surgery, Vice Chair of Quality and Safety in the Department of Surgery, and Co-chair of the Department's Research Committee. Dr. Wick is an experienced laparoscopic surgeon and treats the entire spectrum of colorectal conditions including diverticular disease, inflammatory bowel disease, colon and rectal cancer, anal cancer, and perianal disease with a patient-­‐centered approach.

    Dr. Wick has also contributed to our understanding of almost every aspect of perioperative care from teamwork and communication to organizational culture to quality improvement and measurement. She has been consistently funded by the National Institutes of Health since 2010. She has published over 150 articles around quality and safety and the microbiome and is frequently asked to speak and share her expertise with other hospitals, state hospital associations and professional societies across the United States and abroad.

    She is leading a national collaborative, in partnership with the Agency for Healthcare Research and Quality and the American College of Surgeons, around accelerating dissemination of surgical pathways across 4 surgical areas (colorectal, gynecology, orthopedics and emergency general surgery) over five years. To date, over 300 hospitals have joined the program and engagement and improvement has been remarkable. Recognizing that measurement is essential to evaluating implementation, Dr. Wick is interested in harnessing the electronic health record to better measure performance and is working on automating surgical site infection measurement using advanced informatics (R01).  

    Education

    Institution Degree Dept or School End Date
    Cleveland Clinic Fellowship 2008
    UCSF Medical Center Residency 2007
    Vanderbilt University School of Medicine 2000

    Board Certifications

    American Board of Surgery, General Surgery

    American Board of Colon and Rectal Surgery

     

    Collaboration Interests

    I am interested in:

    • physician scientist

    Clinical Expertise

    Diverticulitis

    Diverticular Disease

    Colon Cancer

    Rectal Cancer

    Recurrent Rectal Cancer

    Anal Cancer

    Colovesicle Fistula

    Hemorrhoids

    Inflammatory Bowel Disease

    Crohn's Disease

    Ulcerative Colitis

    Anal Fissure

    Anal Fistula

    Enterocutaneous Fistula

    Appendicitis

    Carcinoid

    Laparoscopy

    Clinical Trials

    1. I CAN DO Surgical ACP (NCT06090552)
      Related Conditions: End of Life| Start Date: | End Date:

    Grants and Funding

    • Leveraging Advanced Informatics to Automate Data Collection of Healthcare Associated Infections (HAI) and Other Surgical Performance Measures | NIH | 2016-09-30 - 2020-09-29 | Role: Principal Investigator
    • Role of Stat3 in ETBF Mediated Colitis and Tumor Initiation | NIH | 2014-02-05 - 2016-01-31 | Role: Principal Investigator
    • Role of Stat3 in Colonic Inflammation | NIH | 2010-07-01 - 2015-12-31 | Role: Principal Investigator

    Research Narrative

    Dr. Wick is a recognized national leader in research to reduce surgical site infections and formulating strategies for improving perioperative care. She has published more than 75 articles in this area and is frequently invited to speak and share her expertise with other hospitals. Most recently, she led an AHRQ-funded national collaborative to improve surgical safety and reduce surgical site infections in 250 hospitals across the US and abroad. 

    Research Interests

    Safety culture

    Perioperative improvement

    Comprehensive unit based safety program (CUSP)

    Teamwork

    Surgical outcomes

    Surgical site infections

    Enhanced recovery

    Clinical pathways

     

    Publications

    MOST RECENT PUBLICATIONS FROM A TOTAL OF 262
    1. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses.
      Wu S, Rhee KJ, Albesiano E, Rabizadeh S, Wu X, Yen HR, Huso DL, Brancati FL, Wick E, McAllister F, Housseau F, Pardoll DM, Sears CL| | PubMed
    2. Surgical site infections in a "high outlier" institution: are colorectal surgeons to blame?
      Wick EC, Vogel JD, Church JM, Remzi F, Fazio VW| | PubMed
    3. Contemporary surgical management for ileosigmoid fistulas in Crohn's disease.
      Melton GB, Stocchi L, Wick EC, Appau KA, Fazio VW| | PubMed
    4. Implementation of quality measures to reduce surgical site infection in colorectal patients.
      Wick EC, Gibbs L, Indorf LA, Varma MG, Garcia-Aguilar J| | PubMed
    5. MUC5AC, a gel-forming mucin accumulating in gallstone disease, is overproduced via an epidermal growth factor receptor pathway in the human gallbladder.
      Finzi L, Barbu V, Burgel PR, Mergey M, Kirkwood KS, Wick EC, Scoazec JY, Peschaud F, Paye F, Nadel JA, Housset C| | PubMed
    6. Comparison of superior mesenteric versus jugular venous infusions of insulin in streptozotocin-diabetic rats on the choice of caloric intake, body weight, and fat stores.
      Warne JP, Horneman HF, Wick EC, Bhargava A, Pecoraro NC, Ginsberg AB, Akana SF, Dallman MF| | PubMed
    7. Calcitonin gene-related peptide partially mediates nociception in acute experimental pancreatitis.
      Wick EC, Pikios S, Grady EF, Kirkwood KS| | PubMed
    8. Transient receptor potential vanilloid 1, calcitonin gene-related peptide, and substance P mediate nociception in acute pancreatitis.
      Wick EC, Hoge SG, Grahn SW, Kim E, Divino LA, Grady EF, Bunnett NW, Kirkwood KS| | PubMed
    9. Localization of calcitonin receptor-like receptor and receptor activity modifying protein 1 in enteric neurons, dorsal root ganglia, and the spinal cord of the rat.
      Cottrell GS, Roosterman D, Marvizon JC, Song B, Wick E, Pikios S, Wong H, Berthelier C, Tang Y, Sternini C, Bunnett NW, Grady EF| | PubMed
    10. Neutral endopeptidase determines the severity of pancreatitis-associated lung injury.
      Day AL, Wick E, Jordan TH, Jaffray CE, Bunnett NW, Grady EF, Kirkwood KS| | PubMed